To have an unwanted negative influence on someone, to be distractive to or for someone, impress someone or something in a troublesome or uneasy way.
To make someone rather angry or impatient; to cause annoyance.
cause annoyance in; disturb, esp. by minor irritations: "Mosquitoes buzzing in my ear really bothers me"; "It irritates me that she never closes the door after she leaves"
cause to be in a worse state; "Aspirin irritates my stomach"
excite to an abnormal condition, of chafe or inflame; "Aspirin irritates my stomach"
excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus; "irritate the glands of a leaf"
cause annoyance in; disturb, especially by minor irritations; "Mosquitoes buzzing in my ear really bothers me"; "It irritates me that she never closes the door after she leaves"
excite to an abnormal condition, or chafe or inflame
excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus
cause annoyance in; disturb, especially by minor irritations